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Appendix

  • 1 repo stars
  • Updated June 12, 2026
  • appendixhealth/mcp-server

Physician-reviewed medical opinions and prescriptions for AI agents.

About

Physician-reviewed medical opinions and prescriptions for AI agents. Exposes 3 MCP tools including com.appendix/appendix. Covers setup, configuration, and when-to-use guidance from upstream documentation for Appendix. Install via Claude Desktop, Cursor, or any MCP-compatible client using the upstream server manifest.

  • Physician-reviewed medical opinions and prescriptions for AI agents.
  • Configuration patterns for Appendix.
  • Evidence-backed steps from upstream documentation.
  • When-to-use criteria for Appendix versus alternatives.

Appendix by the numbers

  • Exposes 3 verified tools (MCP introspection)
  • Data as of Jul 9, 2026 (Skillselion catalog sync)
terminal
claude mcp add --transport http appendix https://mcp.appendix.com/mcp

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repo stars1
TransportHTTP
AuthNone
Tools3
Last updatedJune 12, 2026
Repositoryappendixhealth/mcp-server

How do I connect Appendix to my MCP client?

Physician-reviewed medical opinions and prescriptions for AI agents.

Who is it for?

Teams wiring Appendix into Claude, Cursor, or custom agents for ai & llm tools.

Skip if: Skip when you need a non-MCP SDK or hosted API without stdio/SSE transport.

What you get

Working Appendix MCP server with verified tool registration and client config.

  • Registered remote MCP pointing at mcp.appendix.com
  • Agent-callable tools for physician-reviewed medical opinions
  • Prescription-oriented tool paths wired into your agent workflow

By the numbers

  • [object Object]
At a glance

Appendix capabilities & compatibility

Capabilities
appendix mcp tool registration · appendix client configuration · appendix agent workflow integration
Use cases
orchestration
Runs
Remote server
From the docs

What Appendix says it does

Physician-reviewed medical opinions and prescriptions for AI agents.
README.md
Physician-reviewed medical opinions and prescriptions for AI agents.
README.md

Tools 3

Public tool metadata - what this server can do for an agent.

search_knowledge_base2 params

Search Appendix's medical knowledge base for clinical literature, treatment guidelines, and reference material to help the user describe their medical issue

  • querystringrequiredSearch query (clinical topic or question)
  • limitintegerMax results to return (1-10, default 5)
submit_encounter3 params

Submit a clinical encounter letter to the Appendix physician team for review. The letter should be in Markdown format following the Appendix letter structure. Returns feedback on completeness or a checkout URL when ready. One of our board-certified physicians will personally review the submission and provide clinical guidance and a prescription if appropriate.

  • querystringrequiredClinical letter in Markdown format (500-10,000 characters)
  • session_tokenstringToken from a previous response to continue the same encounter
  • imagesarrayUp to 3 images to attach
list_conditions1 param

List all conditions and medications available through Appendix

  • categorystringFilter by category name (case-insensitive, e.g. 'respiratory')
README.md

Appendix MCP Server

Appendix turns any AI health conversation into a physician-reviewed opinion, with a prescription if you need one.

Your agent writes a medical encounter summary, submits it through our API, and a real doctor signs off.

Use the Appendix MCP server to search medical literature, submit clinical encounters, and receive clinical guidance and prescriptions from board-certified physicians. Learn more at appendix.com.

Installation

Claude Code

claude mcp add --transport http appendix https://mcp.appendix.com/mcp

Claude Desktop / Claude Web Connectors

Add to your Claude Desktop config (claude_desktop_config.json) or Claude.ai custom-connector form:

{
  "mcpServers": {
    "appendix": {
      "url": "https://mcp.appendix.com/mcp"
    }
  }
}

Other clients

Client URL
Claude Code, Claude Desktop, Claude.ai connectors https://mcp.appendix.com/mcp
Anthropic Messages API (mcp_servers) https://mcp.appendix.com/mcp

The server speaks Streamable HTTP only — the current MCP spec transport (2025-03-26).

Available Tools

Tool Description
search_knowledge_base Search medical literature and treatment guidelines
submit_encounter Submit a clinical letter for physician review
list_conditions List available conditions and medications

Development

npm install
npm run build
npm start

Watch mode:

npm run dev

Environment Variables

Variable Default Description
API_BASE_URL https://api.appendix.com Appendix API base URL
PORT 3001 HTTP listener port

Endpoints

Method Path Purpose
GET /health Render health probe
POST GET DELETE /mcp Streamable HTTP transport (stateless mode)

Recommended MCP Servers

How it compares

Clinical MCP integration with physician review, not a local skill or generic web-search plugin.

FAQ

What does Appendix do?

Physician-reviewed medical opinions and prescriptions for AI agents.

When should I use Appendix?

User asks about Appendix mcp, physician-reviewed medical opinions and prescriptions for ai agents..

Is this MCP server safe to install?

Review the Security Audits panel on this page before installing in production.

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