Tooluniverse
- 1.6k repo stars
- Updated July 27, 2026
- mims-harvard/ToolUniverse
Gives an AI-scientist agent access to 1000+ scientific tools (life science, literature, drug/gene/disease databases) via a compact tool-finder, for research at scale.
About
ToolUniverse is an MCP server from Harvard exposing 1000-plus scientific tools for AI scientists across life science, literature, and biomedical databases. A researcher or solo builder reaches for it to search papers and query gene, disease, protein, and patent datasets from an agent. It runs via uvx as a PyPI package in a compact mode that surfaces a tool-finder and executor to avoid context overflow, with optional API keys unlocking specialized data sources.
- 1000+ scientific tools for AI scientists
- Compact mode: 4 core tools + tool-finder to avoid context overflow
- uvx/pypi tooluniverse stdio server
- Optional keys for PubMed, UMLS, OncoKB, NVIDIA NIM, and more
Tooluniverse by the numbers
- Data as of Jul 28, 2026 (Skillselion catalog sync)
claude mcp add --env OPENAI_API_KEY=YOUR_OPENAI_API_KEY --env ANTHROPIC_API_KEY=YOUR_ANTHROPIC_API_KEY --env GEMINI_API_KEY=YOUR_GEMINI_API_KEY --env OPENROUTER_API_KEY=YOUR_OPENROUTER_API_KEY --env AZURE_OPENAI_API_KEY=YOUR_AZURE_OPENAI_API_KEY --env HF_TOKEN=YOUR_HF_TOKEN --env NCBI_API_KEY=YOUR_NCBI_API_KEY --env SEMANTIC_SCHOLAR_API_KEY=YOUR_SEMANTIC_SCHOLAR_API_KEY --env BIOGRID_API_KEY=YOUR_BIOGRID_API_KEY --env DISGENET_API_KEY=YOUR_DISGENET_API_KEY --env OMIM_API_KEY=YOUR_OMIM_API_KEY --env ONCOKB_API_TOKEN=YOUR_ONCOKB_API_TOKEN --env NVIDIA_API_KEY=YOUR_NVIDIA_API_KEY --env USPTO_API_KEY=YOUR_USPTO_API_KEY --env UMLS_API_KEY=YOUR_UMLS_API_KEY --env BRENDA_EMAIL=YOUR_BRENDA_EMAIL --env BRENDA_PASSWORD=YOUR_BRENDA_PASSWORD tooluniverse -- uvx tooluniverse tooluniverse-smcp-stdio --compact-mode CATEGORYAdd your badge
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| repo stars | ★ 1.6k |
|---|---|
| Package | tooluniverse |
| Transport | STDIO |
| Auth | Required |
| Last updated | July 27, 2026 |
| Repository | mims-harvard/ToolUniverse ↗ |
What it does
Gives an AI-scientist agent access to 1000+ scientific tools (life science, literature, drug/gene/disease databases) via a compact tool-finder, for research at scale.
Who is it for?
AI-driven scientific and biomedical research
Skip if: General-purpose non-scientific tasks
What you get
- Scientific and biomedical query results
By the numbers
- Exposes 1000+ scientific tools
- Compact mode surfaces just 4 core tools
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