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Hcls Agents

  • 265 repo stars
  • Updated August 5, 2026
  • aws-samples/amazon-bedrock-agents-healthcare-lifesciences

HCLS domain skills and MCP tools for building healthcare and life sciences agents on AWS

Key points

  • AI agent integration
  • Comprehensive tool coverage
  • Production-ready features

Hcls Agents by the numbers

  • Data as of Aug 5, 2026 (Skillselion catalog sync)
/plugin marketplace add aws-samples/amazon-bedrock-agents-healthcare-lifesciences
/plugin install hcls-agents@amazon-bedrock-agents-healthcare-lifesciences

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repo stars265
Last updatedAugust 5, 2026
Repositoryaws-samples/amazon-bedrock-agents-healthcare-lifesciences

What it does

HCLS domain skills and MCP tools for building healthcare and life sciences agents on AWS

README.md

HCLS Agents Plugin

Healthcare and Life Sciences domain skills and MCP tools for AI coding assistants.

What This Plugin Provides

  • Domain skills — workflow guidance for genomics, drug discovery, clinical trials, biomarker analysis, medical terminology, and more
  • MCP tools — connections to biomedical databases, ontology services, literature search, and genomics platforms
  • Agent patterns — references to 36+ production-ready HCLS agents in the catalog

Installation

Claude Code

/plugin marketplace add aws-samples/amazon-bedrock-agents-healthcare-lifesciences
/plugin install hcls-agents

Codex

codex plugin marketplace add aws-samples/amazon-bedrock-agents-healthcare-lifesciences
codex plugin install hcls-agents

Kiro, Cursor, Amazon Quick

See platforms/ for per-tool setup instructions, or run:

./platforms/setup.sh

Use With AWS Agent Toolkit

This plugin provides domain knowledge (WHAT to build for healthcare/life sciences). For infrastructure skills (HOW to deploy on AWS), install the AWS Agent Toolkit alongside:

/plugin marketplace add aws/agent-toolkit-for-aws
/plugin install aws-agents

Together:

  • HCLS skills guide domain workflows (variant interpretation, trial matching, biomarker analysis)
  • AWS Agent Toolkit skills handle infrastructure (deploy to AgentCore, create IAM roles, configure guardrails)
  • AWS MCP servers execute infrastructure actions when HCLS skills need them (HealthOmics for genomics, Athena for data, S3 for storage)

MCP Servers Included

The default .mcp.json connects to:

  • AWS Knowledge — AWS documentation and architecture guidance
  • AgentCore Docs — Bedrock AgentCore API reference
  • Strands Docs — Strands Agents SDK documentation
  • AWS HealthOmics — 60+ genomics workflow management tools

Additional MCP servers (biomedical databases, ontologies, literature) are available in mcp-servers/ — see their READMEs for setup.

Skills

Skills are located in the top-level skills/ directory. Each skill contains:

  • SKILL.md — workflow instructions with YAML frontmatter
  • scripts/ — executable code the AI assistant can run
  • references/ — domain documentation loaded on-demand

See skills/ for the full catalog of available skills.

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