Clinical Decision Support
Generate structured genomic/clinical profile reports with tiered evidence and variant sections for decision-support workflows.
Overview
Clinical Decision Support is an agent skill for the Build phase that structures genomic profile and clinical decision-support style reports using a formal LaTeX template.
Install
npx skills add https://github.com/k-dense-ai/scientific-agent-skills --skill clinical-decision-supportWhat is this skill?
- LaTeX genomic profile report scaffold with patient ID header and pagination
- Color-coded tier semantics (tier1/tier2/tier3) for evidence or action levels
- Variant class styling for mutation, amplification, and fusion callouts
- Compact clinical one-page oriented layout (letter, 0.5in margins)
- Agent-oriented scientific skill packaging for CDS-style deliverables
- 3 tier color roles in template: tier1, tier2, tier3
- 3 variant highlight classes: mutation, amplification, fusion
Adoption & trust: 524 installs on skills.sh; 27.6k GitHub stars; 2/3 security scanners passed (skills.sh audits).
What problem does it solve?
You have genomic or clinical findings but no consistent, professional report layout for tiered recommendations and variant highlights.
Who is it for?
Builders of scientific or health-adjacent agents who need reproducible CDS-style PDF/report shells.
Skip if: Replacing licensed clinicians, unvalidated diagnostic claims, or teams without compliance review for patient-facing medical content.
When should I use this skill?
Producing structured genomic profile or clinical decision-support reports from agent workflows that need tiered, variant-aware document layout.
What do I get? / Deliverables
You get a LaTeX-based genomic profile report structure with tier and variant visual encoding ready to fill with patient-specific data.
- Genomic profile LaTeX report draft
- Tiered and variant-formatted clinical summary layout
Recommended Skills
Journey fit
Clinical decision-support artifacts are built when you turn research outputs into standardized reports agents or clinicians can consume. Docs subphase fits templated report generation (LaTeX genomic profile layout) rather than live clinical deployment or validation study design.
How it compares
Use for templated clinical report generation, not for general medical Q&A or HIPAA-ready production systems by itself.
Common Questions / FAQ
Who is clinical-decision-support for?
Indie builders and researchers automating genomic profile or clinical summary documents with agent assistance, alongside qualified domain review.
When should I use clinical-decision-support?
Use it in Build when drafting structured genomic profile reports with tiered evidence blocks and variant sections before human clinical sign-off.
Is clinical-decision-support safe to install?
Review the Security Audits panel on this Prism page; treat all generated clinical content as non-authoritative until validated by appropriate professionals and policies.
SKILL.md
READMESKILL.md - Clinical Decision Support
\documentclass[10pt,letterpaper]{article} % Packages \usepackage[margin=0.5in]{geometry} \usepackage[utf8]{inputenc} \usepackage[T1]{fontenc} \usepackage{helvet} \renewcommand{\familydefault}{\sfdefault} \usepackage{xcolor} \usepackage{tcolorbox} \usepackage{array} \usepackage{tabularx} \usepackage{booktabs} \usepackage{enumitem} \usepackage{titlesec} \usepackage{fancyhdr} \usepackage{graphicx} % Color definitions \definecolor{headerblue}{RGB}{0,102,204} \definecolor{tier1green}{RGB}{0,153,76} \definecolor{tier2orange}{RGB}{255,152,0} \definecolor{tier3gray}{RGB}{158,158,158} \definecolor{mutationred}{RGB}{244,67,54} \definecolor{amplificationblue}{RGB}{33,150,243} \definecolor{fusionpurple}{RGB}{156,39,176} \definecolor{highlightgray}{RGB}{240,240,240} % Section formatting \titleformat{\section}{\normalfont\fontsize{11}{12}\bfseries\color{headerblue}}{\thesection}{0.5em}{} \titlespacing*{\section}{0pt}{4pt}{2pt} \titleformat{\subsection}{\normalfont\fontsize{10}{11}\bfseries}{\thesubsection}{0.5em}{} \titlespacing*{\subsection}{0pt}{3pt}{1pt} % List formatting \setlist[itemize]{leftmargin=*,itemsep=0pt,parsep=0pt,topsep=1pt} \setlist[enumerate]{leftmargin=*,itemsep=0pt,parsep=0pt,topsep=1pt} \setlength{\parindent}{0pt} \setlength{\parskip}{2pt} % Header/footer \pagestyle{fancy} \fancyhf{} \fancyhead[L]{\footnotesize \textbf{Genomic Profile Report: [PATIENT ID]}} \fancyhead[R]{\footnotesize Page \thepage} \renewcommand{\headrulewidth}{0.5pt} \fancyfoot[C]{\footnotesize Confidential Laboratory Report - CLIA/CAP Certified} \begin{document} % Title block \begin{center} {\fontsize{14}{16}\selectfont\bfseries\color{headerblue} COMPREHENSIVE GENOMIC PROFILING REPORT}\\[2pt] {\fontsize{10}{12}\selectfont [Laboratory Name] | CLIA \#: [Number] | CAP \#: [Number]} \end{center} \vspace{2pt} % Patient/Specimen Information \begin{tcolorbox}[colback=highlightgray,colframe=black] \begin{minipage}{0.48\textwidth} {\small \textbf{Patient Information}\\ Patient ID: [De-identified ID]\\ Date of Birth: [De-identified/Age only]\\ Sex: [M/F]\\ Ordering Physician: [Name, MD] } \end{minipage} \hfill \begin{minipage}{0.48\textwidth} {\small \textbf{Specimen Information}\\ Specimen Type: [Tissue/Blood/Other]\\ Collection Date: [Date]\\ Received Date: [Date]\\ Report Date: [Date] } \end{minipage} \end{tcolorbox} \vspace{2pt} % Diagnosis \textbf{Diagnosis}: [Cancer type, stage, histology] \textbf{Testing Performed}: [Assay name - e.g., FoundationOne CDx, NGS Panel] \vspace{2pt} % Results Summary Box \begin{tcolorbox}[enhanced,colback=tier1green!10,colframe=tier1green, title=\textbf{RESULTS SUMMARY},fonttitle=\bfseries,coltitle=black] {\small \textbf{Actionable Findings}: [X] alteration(s) detected \begin{itemize} \item \textbf{Tier 1}: [Number] FDA-approved therapy target(s) \item \textbf{Tier 2}: [Number] clinical trial or off-label option(s) \item \textbf{Tier 3}: [Number] variant(s) of uncertain significance \end{itemize} \textbf{Additional Biomarkers}: \begin{itemize} \item Tumor Mutational Burden (TMB): [X.X] mutations/Mb - [High/Intermediate/Low] \item Microsatellite Status: [MSI-H / MSS / Not assessed] \item PD-L1 Expression: [X\% TPS / Not assessed] \end{itemize} } \end{tcolorbox} \section{Tier 1: FDA-Approved Targeted Therapies} \begin{tcolorbox}[enhanced,colback=tier1green!5,colframe=tier1green, title={\colorbox{mutationred!60}{\textcolor{white}{\textbf{MUTATION}}} \textbf{[Gene Name] [Alteration]} \hfill \textbf{TIER 1 - ACTIONABLE}}, fonttitle=\bfseries\small,coltitle=black] {\small \textbf{Alteration}: [Gene] [Specific variant - e.g., EGFR p.L858R (c.2573T>G)]\\ \textbf{Variant Allele Frequency (VAF)}: XX\% (suggests [clonal/subclonal] mutation)\\ \textbf{Classification}: [Pathogenic / Likely Pathogenic] (ClinVar, OncoKB) \textbf{Clinical Significance}: \textcolor{tier1green}{\textbf{ACTIONABLE - FDA-APPROVED THERAPY AVAILABLE}} \textbf{FDA-Approved Therapy}: \begin{itemize} \item \textbf{Drug}: [Drug name (brand name)]